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進捗状況

  • 各チームが決定した各サンプルの標準エピゲノムデータは IHEC へ登録されます。
  • 日本チームが IHEC へ登録した標準エピゲノムデータ(EpiRR)の状況はこちらです。
    「Complete」は IHEC が求める項目(WGBS、RNA-seq、ChIP-seq 6種)が揃っているデータです。

論文

金井チーム

  • Miura F, Enomoto Y, Dairiki R, Ito T. Amplification-free whole-genome bisulfite sequencing by post-bisulfite adaptor tagging. Nucleic Acids Res. (2012) 40: e136.
  • Tian Y, Arai E, Gotoh M, Komiyama M, Fujimoto H, Kanai Y. Prognostication of patients with clear cell renal cell carcinomas based on quantification of DNA methylation levels of CpG island methylator phenotype marker genes. BMC Cancer. (2014) 14, 772.

白髭チーム

  • Nakato R, Itoh T, Shirahige K. DROMPA: easy-to-handle peak calling and visualization software for the computational analysis and validation of ChIP-seq data. Genes to Cells. (2013) 18, 589–601.
  • Saito Y, Tsuji J, Mituyama T. Bisulfighter: accurate detection of methylated cytosines and differentially methylated regions. Nucleic Acids Research. (2014) 42, e45.
  • Nozawa R, Nagao K, Igami K, Shibata S, Shirai N, Nozaki N, Sado T, Kimura H, Obuse C. Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway. Nat Struct Mol Biol. (2013) 20, 566–573.

佐々木チーム

  • Hamada H, Okae H, Toh H, Chiba H, Hiura H, Shirane K, Sato T, Suyama M, Yaegashi N, Sasaki H, Arima T. Allele-specific methylome and transcriptome analysis reveals widespread imprinting in the human placenta. Am J Hum Genet. (2016) 99, 1045–1058.
  • Toh H, Shirane K, Miura F, Kubo N, Ichiyanagi K, Hayashi K, Saitou M, Suyama M, Ito T, Sasaki H. Software updates in the Illumina HiSeq platform affect whole-genome bisulfite sequencing. BMC Genomics. (2017) 18, 31.